Applied behavior analysis (ABA) and therapies based on its principles are the most researched and commonly used behavioral interventions for autism. Research has shown that ABA therapy is the most effective treatment method resulting in higher functioning and greater independence in living, especially among those who have received ABA therapy as children.

Genesis Autism Center has a focus on Happy, Relaxed, and Engaged (HRE) ABA to teach learners with Autism, intellectual disabilities, and developmental delays. ABA strives to improve socially significant behaviors that assist learners with improving independence and skills in areas such as: